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Research
Biophysics

 

Jean-Paul Armache

  • Mechanisms and functions of ATP-dependent chromatin remodeling complexes and their place in genome regulation. 

Lu Bai

  • Chromatin structure and its role in gene regulation.

Squire Booker

  • Elucidating the chemical mechanisms by which enzymes containing iron-sulfur clusters catalyze chemical reactions.

Paul Cremer

  • The exploitation of linear and non-linear vibrational spectroscopies to follow the interactions of ions with peptides, proteins, and macromolecules.

John Golbeck

  • Biophysical studies of electron transfer mechanisms in photosynthetic prokaryotes.

Carsten Krebs

  • The elucidation of the reaction mechanisms by which mono- and dinuclear non-heme-iron enzymes activate dioxygen (O2) for a wide variety of oxidative transformations.

Manuel Llinás

  • The combination of tools from functional genomics, molecular biology, computational biology, biochemistry, and metabolomics to understand the fundamental molecular mechanisms underlying the development of this parasite.

Katsuhiko Murakami

  • We apply cryo-EM and X-ray crystallography techniques to reveal three-dimensional structures of DNA and RNA polymerases for elucidating the mechanisms of DNA replication and RNA transcription.

Denise Okafor

  • The structural mechanisms of signaling and regulation in protein complexes.

Scott Showalter

  • The use of solution nuclear magnetic resonance (NMR) spectroscopy, in combination with thermodynamic analysis, chemical biology, and cellular assays to advance understanding of protein function.

Song Tan

  • The understanding of how genes are regulated by combining genetic, biochemical and structural descriptions

Emily Weinert

  • The understanding of how the globin coupled sensor protein family senses oxygen and transmits the binding signal into downstream events

Hemant Yennawar

  • Elucidating molecular structures relevant to chemists, biochemists, material scientists etc. and educating graduate students embarking in these fields, the technique of X-ray diffraction (crystal growth, data collection and structure solution and refinement, and interpretation).