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Research
Cell and Developmental Biology

Santhosh Girirajan

  • Eukaryotic transcriptional regulation

Ying Gu

  • The utilization of biochemical, molecular genetics, and spectroscopic approaches to decipher mechanisms of cellulose biosynthesis.

Wendy Hanna-Rose

  • We use genetic and metabolomics approaches in C. elegans to model inborn errors of metabolism and probe the molecular links between metabolic perturbations and animal behavior and physiology.

Teh-hui Kao

  • The study of self-incompatibility (SI), a self/non-self recognition mechanism between pollen and pistils, which was first well documented by Charles Darwin in a monograph published in 1865.

Zhi-Chun Lai

  • Growth Control and Cancer Genetics

Scott Lindner

  • The coupling of molecular parasitology and structural biology to study the malaria parasite.

Bernard Lüscher

  • Molecular and cellular mechanisms underlying neuropsychiatric disorders as well as mechanisms of antidepressant drug therapies.
     

Timothy Miyashiro

  • We use microbial genetics, biochemistry, and cell biology approaches to determine the molecular mechanisms that enable bacteria to establish symbiosis with a eukaryotic host.  The model system is the symbiosis formed between the bioluminescent bacterium Vibrio fischeri and the Hawaiian bobtail squid Euprymna scolopes.  Our primary interests in this system include quorum sensing, contact-dependent killing mechanisms, and sulfur metabolism.

Robert Paulson

  • The mechanism of tissue regeneration using the response to anemia as a model system.

Frank Pugh

  • Genomic mechanisms of eukaryotic gene regulation.

Melissa Rolls

  • The Rolls lab aims to understand how neurons generate axons and dendrites with different microtubule organization, and how neurons respond to injury. Current projects focus on mechanisms that control microtubule polarity and dynamics and mechanisms that promote neuronal regeneration.

Lorraine Santy

  • We study the signal transduction and vesicular trafficking processes that promote migration in epithelial cells.  We seek to understand the role of these processes in normal homeostasis and in pathological processes.

Scott Selleck

  • Nervous system development and molecular mechanisms of neurodegenerative disorders

Scott Showalter

  • The use of solution nuclear magnetic resonance (NMR) spectroscopy, in combination with thermodynamic analysis, chemical biology, and cellular assays to advance understanding of protein function.

Moriah Szpara

  • Understanding the consequences of HSV latency for the neurons that harbor the HSV pathogen and the search for improved therapeutics using a combination of virology, neurobiology, next generation sequencing technologies, and bioinformatics.

Claire Thomas

  • The role of the cortical actin cytoskeleton in cell polarity and morphogenesis.