Many themes of Biochemistry and Molecular Biology (BMB) are woven into the department’s research contributions in neurobiology. Faculty in BMB study the molecular processes that underlie the development of the nervous system, as well as how these processes can go awry due to genetic variations or infectious diseases. Faculty research in neurobiology reaches from human clinical studies to model organisms and cell-based studies, using methods that include molecular, genetic, biochemical, and computational methods to advance neurobiology research at Penn State.
- Molecular and cellular mechanisms underlying neuropsychiatric disorders as well as mechanisms of antidepressant drug therapies.
- The Rolls lab aims to understand how neurons generate axons and dendrites with different microtubule organization, and how neurons respond to injury. Current projects focus on mechanisms that control microtubule polarity and dynamics and mechanisms that promote neuronal regeneration.
- Nervous system development and molecular mechanisms of neurodegenerative disorders
- Understanding the consequences of HSV latency for the neurons that harbor the HSV pathogen and the search for improved therapeutics using a combination of virology, neurobiology, next generation sequencing technologies, and bioinformatics.