About Me
Dr. Yennawar had his education in India, obtaining Bachelors and Masters degrees in Science from Nagpur University and PhD in Physics (X-ray crystallography) from Indian Institute of Science Bangalore. He joined Penn State University as a post-doctoral fellow to work in the protein crystallography laboratory and later appointed as the director of X-ray crystallography facility for the BMB & Chemistry Departments (1997).
Department or University Committees
Program or Departmental Affiliations
Research Summary
Dr. Yennawar’s research activity primarily involves elucidating molecular structures using X-ray diffraction technique - which can be relevant to biochemistry, chemistry, biology, material science, veterinary science, etc.
As in-charge of the X-ray lab, Dr. Yennawar maintains different X-ray instrumentation (Rigaku MicroMax 007 for macromolecular single crystal and Bruker Smart Apex for small molecule single crystal diffractometers.
Dr. Yennawar has collaborated extensively with other researchers (faculty, post-doctoral fellows and graduate students) extensively. His collaborators are from various departments - BMB, Chemistry, Material Research Laboratory here on the main campus and from Penn State sister campuses as well. Much of the work has been published in peer-reviewed journals. PubMed search shows about sixty papers in various disciplines of research, to his credit.
As outreach service, the facility accepts samples from private industry, for which a separate fee structure is established.
In addition to guiding and training young researchers in the laboratory, Dr. Yennawar teaches the ‘Biomolecular Structure’ (BMMB 598-003) course in the spring semester, for which he has gotten the ‘most highly rated faculty’ recognition from the Dean’s office.
Honors and Awards
- Office of Dean (ECoS) recognition: SRTE Most Highly Rated Faculty (2012)
Selected Publications
- Crystal structures of two solvated 2-aryl-3-phenyl-2,3-di-hydro-4H-pyrido[3,2-e][1,3]thia-zin-4-ones. Yennawar HP, Thompson EN, Li J, Silverberg LJ. Acta Crystallogr E Crystallogr Commun. 2019 Oct 22;75(Pt 11):1689-1693. doi: 10.1107/S2056989019013781. eCollection 2019 Nov 1.
- Crystal structures of three hexakis-(fluoroar-yloxy)cyclo-triphosphazenes. Yennawar HP, Hess AR, Allcock HR. Acta Crystallogr E Crystallogr Commun. 2019 Sep 27;75(Pt 10):1525-1530. doi: 10.1107/S2056989019012933. eCollection 2019 Oct 1.
- Crystal structures of two isomeric 2-aryl-3-phenyl-1,3-thia-zepan-4-ones. Yennawar HP, Peterson SD, Silverberg LJ. Acta Crystallogr E Crystallogr Commun. 2019 Jul 26;75(Pt 8):1270-1273. doi: 10.1107/S2056989019010429. eCollection 2019 Aug 1.
- Crystal structure of a 1:1 adduct of tri-phenyl-tin chloride with 3-cyclo-hexhyl-2-phenyl-1,3-thia-zolidin-4-one. Yennawar HP, Tierney J, Cannon KC. Acta Crystallogr E Crystallogr Commun. 2019 Feb 8;75(Pt 3):338-341. doi: 10.1107/S2056989019001592. eCollection 2019 Mar 1.
- Crystal structures of two 1,3-thia-zolidin-4-one derivatives featuring sulfide and sulfone functional groups. Yennawar HP, Silverberg LJ, Cannon K, Gandla D, Kondaveeti SK, Zdilla MJ, Nuriye A. Acta Crystallogr E Crystallogr Commun. 2018 Nov 6;74(Pt 12):1695-1699. doi: 10.1107/S2056989018015098. eCollection 2018 Dec 1.
- Crystal structures of two thia-zolidinone derivatives bearing a tri-chloro-methyl substituent at the 2-position. Nuriye A, Yennawar H, Cannon K, Tierney J. Acta Crystallogr E Crystallogr Commun. 2018 Sep 28;74(Pt 10):1509-1512. doi: 10.1107/S2056989018013257. eCollection 2018 Oct 1.
- Crystal structure of meso-3,3'-(1,4-phenyl-ene)bis-(2-phenyl-2,3,5,6-tetra-hydro-4H-1,3-thia-zin-4-one). Yennawar HP, Moyer QJ, Silverberg LJ. Acta Crystallogr E Crystallogr Commun. 2018 Sep 28;74(Pt 10):1497-1499. doi: 10.1107/S2056989018013397. eCollection 2018 Oct 1.
- Modulation of Fluorescent Protein Chromophores To Detect Protein Aggregation with Turn-On Fluorescence. Liu Y, Wolstenholme CH, Carter GC, Liu H, Hu H, Grainger LS, Miao K, Fares M, Hoelzel CA, Yennawar HP, Ning G, Du M, Bai L, Li X, Zhang X. J Am Chem Soc. 2018 Jun 20;140(24):7381-7384. doi: 10.1021/jacs.8b02176. Epub 2018 Jun 12.
- Spontaneous resolution and crystal structure of (2S)-2-(3-nitro-phen-yl)-3-phenyl-2,3,5,6-tetra-hydro-4H-1,3-thia-zin-4-one; crystal structure of rac-2-(4-nitro-phen-yl)-3-phenyl-2,3,5,6-tetra-hydro-4H-1,3-thia-zin-4-one. Yennawar HP, Bradley HG, Perhonitch KC, Reppert HE, Silverberg LJ. Acta Crystallogr E Crystallogr Commun. 2018 Mar 6;74(Pt 4):454-457. doi: 10.1107/S2056989018003444. eCollection 2018 Apr 1.
- Crystal structures of two 2,3-diaryl-2,3-di-hydro-4H-1,3-benzo-thia-zin-4-ones. Yennawar HP, Buchwalter MJ, Colburn BK, Silverberg LJ. Acta Crystallogr E Crystallogr Commun. 2018 Feb 20;74(Pt 3):363-366. doi: 10.1107/S2056989018002049. eCollection 2018 Mar 1.
- Crystal structure of (1S,2S,5R)-5-acetyl-amino-4-oxo-2,3-diphenyl-1,3-thia-zinan-1-ium-1-olate. Yennawar HP, Noble DJ, Silverberg LJ. Acta Crystallogr E Crystallogr Commun. 2017 Sep 5;73(Pt 10):1417-1420. doi: 10.1107/S2056989017012488. eCollection 2017 Oct 1.
- Crystal structure of 2,3-diphenyl-2,3-di-hydro-4H-1,3-benzo-thia-zin-4-one 1-oxide. Yennawar HP, Fox R, Moyer QJ, Yang Z, Silverberg LJ. Acta Crystallogr E Crystallogr Commun. 2017 Jul 17;73(Pt 8):1189-1191. doi: 10.1107/S2056989017010313. eCollection 2017 Jul 1.
- Stable Open-Shell Phosphorane Based on a Redox-Active Amidodiphenoxide Scaffold. Pistner AJ, Moon HW, Silakov A, Yennawar HP, Radosevich AT. Inorg Chem. 2017 Aug 7;56(15):8661-8668. doi: 10.1021/acs.inorgchem.7b00657. Epub 2017 Jun 29.
- P-N Cooperative Borane Activation and Catalytic Hydroboration by a Distorted Phosphorous Triamide Platform. Lin YC, Hatzakis E, McCarthy SM, Reichl KD, Lai TY, Yennawar HP, Radosevich AT. J Am Chem Soc. 2017 Apr 26;139(16):6008-6016. doi: 10.1021/jacs.7b02512. Epub 2017 Apr 18.
- Crystal structure of rac-2,3-diphenyl-2,3,5,6-tetrahydro-4H-1,3-thiazin-4-one 1-oxide. Yennawar HP, Yang Z, Silverberg LJ. Acta Crystallogr E Crystallogr Commun. 2016 Oct 7;72(Pt 11):1541-1543. eCollection 2016 Nov 1.
- Crystal structures of three substituted 3-aryl-2-phenyl-2,3-di-hydro-4H-1,3-benzo-thia-zin-4-ones. Yennawar HP, Coyle DJ, Noble DJ, Yang Z, Silverberg LJ. Acta Crystallogr E Crystallogr Commun. 2016 Jul 12;72(Pt 8):1108-12. doi: 10.1107/S2056989016011002. eCollection 2016 Aug 1.
- Steady-State Spectroscopic Analysis of Proton-Dependent Electron Transfer on Pyrazine-Appended Metal Dithiolenes [Ni(pdt)2], [Pd(pdt)2], and [Pt(pdt)2] (pdt = 2,3-Pyrazinedithiol). Kennedy SR, Kozar MN, Yennawar HP, Lear BJ. Inorg Chem. 2016 Sep 6;55(17):8459-67. doi: 10.1021/acs.inorgchem.6b01065. Epub 2016 Aug 8.
- Crystal structure of the 1:1 adduct of 2,3-diphenyl-3,4,5,6-tetra-hydro-2H-1,3-thia-zin-4-one with tri-phenyl-tin chloride. Yennawar HP, Fox R, Silverberg LJ. Acta Crystallogr E Crystallogr Commun. 2016 Feb 3;72(Pt 3):276-9. doi: 10.1107/S2056989016001730. eCollection 2016 Mar 1.
- Effect of Protonation upon Electronic Coupling in the Mixed Valence and Mixed Protonated Complex, [Ni(2,3-pyrazinedithiol)2]. Kennedy SR, Goyal P, Kozar MN, Yennawar HP, Hammes-Schiffer S, Lear BJ. Inorg Chem. 2016 Feb 15;55(4):1433-45. doi: 10.1021/acs.inorgchem.5b02035. Epub 2016 Jan 26.