Bioinformatics and Genomics
Dr. Armache's Research Interest: Mechanisms and functions of
ATP-dependent chromatin remodeling complexes and their place
in genome regulation.
Dr. Bai's Research Interest: Chromatin structure and its role in
gene regulation.
Dr. Bisanz's Research Interest: The structure and function
of the microbiome and its impacts on health and disease.
Dr. Bryant's Research Interest: Genomics, structural and
functional relationships, metabolism, physiology and ecology
of chlorophototrophic bacteria.
Dr. Ferry's Research Interest: The study the enzymology and
molecular biology of anaerobic microbes from the Archaea
domain.
Dr. Girirajan's Research Interest: Genetics of
neurodevelopmental disorders.
Dr. Hardison's Research Interest: Epigenetic and genomic
approaches for the systematic study of eukaryotic gene
regulation.
Dr. Kao's Research Interest: We use Petunia inflata as a
model to study biochemical, molecular, and structural bases
of a self/non-self recognition mechanism between pollen and
pistil adopted by flowering plants to prevent in breeding and
promote outcrossing.
Dr. Lesk's Research Interest: Computational analysis of protein
structure, function, genomics and evolution.
Dr. Llinás' Research Interest: The combination of tools from
functional genomics, molecular biology, computational biology,
biochemistry, and metabolomics to understand the fundamental
molecular mechanisms underlying the development of this
parasite.
Dr. Mahony's Research Interest: We build machine learning
applications to understand how transcription factors control
cellular identity.
Dr. Medvedev's Research Interest: Developing computer science
techniques for analysis of biological data and on answering
fundamental biological questions using such methods.
Dr. Miyashiro's Research Interest: We use microbial genetics,
biochemistry, and cell biology approaches to determine the
molecular mechanisms that enable bacteria to establish
symbiosis with a eukaryotic host. The model system is the
symbiosis formed between the bioluminescent bacterium Vibrio
fischeri and the Hawaiian bobtail squid Euprymna scolopes.
Our primary interests in this system include quorum sensing,
contact-dependent killing mechanisms, and sulfur metabolism.
Dr. Nekrutenko's Research Interest: Our lab is the birthplace of
Galaxy. It is developed and maintained together with our
collaborators and worldwide community. We also work on a variety
of topics related to mutational dynamics and experimental
evolution. We are also an integral part of the AnVIL project.
Dr. Patterson's Research Interest: Understanding the host-
metabolite-microbiota communication network‚ specifically
how the manipulation of gut microbiota by diet and/or
xenobiotics impacts host metabolites (e.g., bile acids, short
chain fatty acids), their metabolism, and how these co-
metabolites interact with host ligand-activated transcription
factors.
Dr. Roy's Research Interest: Forensic DNA analysis using
massively parallel sequencing and short tandem repeat
technology, trace evidence, fingerprints.
Dr. Szpara's Research Interest: Understanding the consequences
of HSV latency for the neurons that harbor the HSV pathogen
and the search for improved therapeutics using a combination
of virology, neurobiology, next generation sequencing
technologies, and bioinformatics.
