Jordan E. Bisanz

Assistant Professor of Biochemistry and Molecular Biology, Dorothy Foehr and J. Lloyd Huck Early Career Chair in Host-Microbiome Interactions
Jordan Bisanz
Jordan E.
Bisanz
He/Him/His
Assistant Professor of Biochemistry and Molecular Biology, Dorothy Foehr and J. Lloyd Huck Early Career Chair in Host-Microbiome Interactions
Department Affiliations
External Affiliations
Interests
Microbiology
Infectious Disease
Genomics
Bioinformatics
Address
Phone
814-863-1625
Website
http://www.bisanzlab.com

Research Summary

Our group merges computational and experimental approaches to understand how host-associated microbes shape health. We leverage human studies, gnotobiotic animal models, and multi-omics approach to generate and test mechanistic hypotheses at the interface of host and microbe. I am the faculty advisor for the PSU gnotobiotic facility and director of the One Health Microbiome Center co-laboratory, a Qiagen-sponsored facility for high throughput microbiome characterization.

 

Training Background

Postdoctoral fellow/scholar, Advisor: Peter Turnbaugh, UCSF 2015-2021
PhD in Microbiology and Immunology, University of Western Ontario, Advisor: Gregor Reid, 2010-2015
BMSc in Microbiology and Immunology, University of Western Ontario 2006-2010 

 

Graduate Training Programs

Biochemistry, Microbiology, and Molecular Biology 
Molecular, Cell, and Integrative Biosciences Program

 

Selected Publications (see Google Scholar for complete list)

Tian S, MS Kim, J Zhao, K Heber, F Hao, D Koslicki, AD Patterson and JE Bisanz. 2025. A synthetic microbiota designed through meta-analysis provides insight to community function in Clostridioides difficile resistance. Cell Host & Microbe. In Press

Carmody RC and JE Bisanz. 2023. Roles of the gut microbiome in weight management. Nature Reviews Microbiology. 21(8):535-550.

Jumpertz von Schwartzenberg R*, Bisanz JE*,  S Lyalina, P Spanogiannopoulos, QY Ang, J Cai, S Dickman, M Friedrich, S.-Y. Liu, SL Collins, D Ingebrigsten, S Miller, JA Turnbaugh, AD Patterson, KS Pollard, K Mai, J Spranger, and PJ Turnbaugh. 2021. Caloric restriction disrupts the microbiota and colonization resistance. Nature. 595:272-277. *Equal contributions.

Bisanz JE, P Soto Perez, C Noecker, AA Aksenov, KN Lam, EN Bess, HJ Haiser, TS Kyaw, FB Yu, VM Rekdal, CWY Ha, S Devkota, EP Balskus, PC Dorrestein, E Allen-Vercoe, and PJ Turnbaugh. 2020. A genomic toolkit for the mechanistic dissection of intractable human gut bacteria. Cell Host & Microbe. 27(6):1001-1013.

Bisanz JE, V Upadhyay, JA Turnbaugh, and PJ Turnbaugh. 2019. Meta-analysis reveals reproducible gut microbiome alterations in response to a high-fat diet. Cell Host & Microbe. 26(2):265-272.

Bisanz JE, MK Enos, G PrayGod, S Seney, JM Macklaim, S Chilton, D Willner, R Knight, C Fusch, G Fusch, GB Gloor, JP Burton, and G Reid. 2015. The microbiota at multiple body sites during pregnancy in a rural Tanzanian population and the effects of Moringa supplemented probiotic yogurt. Applied and Environmental Microbiology. 81(15):4965-4975.

Bisanz JE, MK Enos, J Mwanga, J Changalucha, JP Burton, GB Gloor, and G Reid. 2014. Randomized open-label pilot study of the influence of probiotics and the gut microbiome on toxic metal levels in Tanzanian pregnant women and school children. mBio. 5(5):e01580-14.

 

Honors and Awards

2024 - Dorothy Foehr and J. Lloyd Huck Early Career Chair in Host-Microbiome Interactions
2023 - Young Investigator Grant in Probiotics Research
2020 - NIAID K99 Postdoctoral Award
2015 - NSERC Postdoctoral Fellowship
2012 - NSERC Alexander Graham Bell Doctoral Canda Graduate Scholarship