Scientists Discover the Origins of Genomic "Dark Matter"
Shown in the upper left corner of this illustration is a chromosome -- a densely compressed package containing one long, continuous strand of DNA. Credit: National Institutes of Health and B. Franklin Pugh, Penn State University
Marylyn Ritchie Honored as an Invited Kavli Fellow for the Third Year in a Row
Marylyn Ritchie
Short-Term Gene-Expression "Memory" is Inherited in Proteins Associated with DNA, New Research Finds
Three fluorescent images of yeast cells as they grow from two single cells (left) to a small cell cluster (right). The green color represents the expression of the HO gene. The red color at the bud neck is a marker for cell cycle. Credit: Bai lab, Penn State University
Using interdisciplinary tools to find cure for human herpesvirus
Paired fluorescence and phase (white light) images of uninfected neurons (top and bottom left) and neurons infected with HSV (top and bottom right). As is clearly visible in the white light images, these neurons form dense networks of connections. Fluorescent dyes can be used to stain and highlight the individual filaments of these networks (top left) as well as to detect a specific viral protein expressed during HSV infection (top right). Image: Moriah Szpara
New Kind of Antibiotic May Be More Effective at Fighting Tuberculosis, Anthrax, and Other Diseases
Bacillus anthracis (anthrax) cells being killed by a molecule studied by Penn State University researcher Kenneth Keiler. The molecule is naturally fluorescent and it looks blue when it is excited by ultraviolet light in the microscope. Keiler and his team found that certain molecules inhibit the growth of very distantly related bacteria by stopping trans-translation, which is a quality control mechanism that is found in all species of bacteria. Credit: Keiler lab, Penn State University
2013 Myriant Corporation Scholarship Winners Announced
2013 Myriant Corporation Scholarship Winners Announced
Probing Question: Do Women Dominate the Field of Forensic Science?
Penn State Forensics students entering a simulation experience.
Gene Offers Clues to New Treatments for a Harmful Blood Clotting Disorder
Shown in blue is chromatin -- the condensed form of DNA that the cell remodels to form chromosomes. The PAD4 enzyme decondenses chromatin by loosening up the interaction between DNA and special proteins called histones. The histones modified by PAD4 are shown in fuchsia. This process helps to form both a bacteria-killing NET -- which is comprised of infection-combatting white blood cells called neutrophils -- and the fluffy, scattered ball that comprises a blood clot. Wang lab, Penn State University.
Autism Linked to Increased Genetic Change in Regions of Genome Instability
These microscopic images were taken as part of research to explore rearrangements of DNA in one of the hotspots of the human genome, where deletions and duplications occur at higher rates. Photo courtesy of Betsy Hirsch/University of Minnesota and Scott Selleck/Penn State University.
Craig E. Cameron Appointed the Eberly Family Chair in Biochemistry and Molecular Biology
Craig Cameron
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