Grayson Sipe

Assistant Professor of Biology
Grayson Sipe
Grayson
Sipe
Assistant Professor of Biology
Department Affiliations
External Affiliations
Interests
Glial Biology
Sensory Processing
Neuromodulation
Stress
Addiction
Address
Website
Sipe Lab
About

Education:

B.S., Neuroscience, Lafayette College

Ph.D., Neurobiology & Anatomy, University of Rochester School of Medicine and Dentistry

 

Postdoctoral Training:

Massachusetts Institute of Technology, 2016-2022

 

Research Summary:

Brain state shifts are critical for functional sensory processing, adaptive decision-making and synaptic plasticity. Our lab studies the molecular and cellular mechanisms underlying brain state shifts at both local circuit and global levels using in vivo microscopy in mice. We study these mechanisms from both neuronal and glial (non-neuronal) perspectives, and integrate their physiology and plasticity with sensory encoding, autonomic regulation, whole-body states and behavior. In addition to studying this physiology under healthy conditions, we are also interested in the pathophysiological mechanisms underlying stress disorders and how these mechanisms contribute to addiction, particularly the development of alcohol abuse.