The inventors have identified promising boron-based compounds that trap phosphatases from the LAR/PTP-sigma/PTP-delta subfamily of the transmembrane PTP. These phosphatases play a role in neuronal development and path finding; they are potential targets for diabetes treatment. -Steve Benkovic.
Inventors from Penn State and Yeshiva University have developed novel therapeutic from a nucleotide analog with unique composition-of-matter that can be used to treat flavivirus infections with a unique mechanism of action that makes them capable of treating both DNA and RNA viruses. -Craig Cameron
Penn State inventors have developed a novel AED to inhibit treat neonatal seizures; proof-of-concept in vitro studies and in vivo animal data demonstrate that this novel potential therapeutic has robust activity and acts as an acute inhibitor of epileptiform activity. -Gong Chen
To combat the challenges of current CO2 electrolysis technology, a novel system was designed where O2 and high value chemicals (fuel products) are created from gaseous CO2 and water.The system uses a bipolar membrane (BPM) based electrochemical cell, similar to current systems available to split water and uses CO2 gas at the cathode, eliminating the problem of separating reaction products from reactants, and minimizes the introduction of contaminants. -Tom Mallouk