Home > Research

Research News at Penn State's Eberly College of Science

Main Content

How to make a motor neuron: Mechanisms underlying direct programming of stem cells could eventually lead to cell-replacement therapies
How to make a motor neuron: Mechanisms underlying direct programming of stem cells could eventually lead to cell-replacement therapies 09 December 2016A team of scientists has uncovered details of the cellular mechanisms that control the direct programming of stem cells into motor neurons. The scientists analyzed changes that occur in the cells over the course of the reprogramming process. They discovered a dynamic, multi-step process in which multiple independent changes eventually converge to change the stem cells into motor neurons.
Key regulator of bone development identified
Key regulator of bone development identified 07 December 2016Loss of a key protein leads to defects in skeletal development including reduced bone density and a shortening of the fingers and toes -- a condition known as brachydactyly. The discovery was made by researchers at Penn State University who knocked out the Speckle-type POZ Protein (Spop) in the mouse and characterized the impact on bone development.

Document Actions

Share this page: |