Peterson Earns Award to Study Protein Interactions Related to Breast Cancer
Blake Peterson, assistant professor of chemistry, has received a Concept Award from the U.S. Army Medical Research and Materiel Command to study protein interactions involved in biochemical resistance of breast cancer to chemotherapy treatments. The award includes a one-time, one-year monetary grant.
His project, approved through a highly competitive, two-tiered review system, proposes to seek ways to inhibit interactions between coactivator proteins and estrogen receptors with synthetic molecules. These protein-protein interactions are thought to allow a majority of tumors to develop resistance to chemotherapy treatments with the anti-cancer drug tamoxifen. With his work, Peterson hopes to chemically synthesize and identify molecules that block interactions between coactivators and estrogen receptors, which would allow the strategy to be further tested in animal models of drug-resistant breast cancer.
Peterson joined the Penn State faculty in 1998. Prior to that, he completed postdoctoral work at Harvard University from 1995 to 1998, served as a research assistant for the Swiss Federal Institute of Technology from 1992 to 1994, and served as a research assistant at the University of California at Los Angeles from 1991 to 1992. He earned his doctoral degree in chemistry at the University of California at Los Angeles in 1994 and his bachelor's degree in chemistry, with distinction, at the University of Nevada at Reno in 1990.
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