Gene Regulation
Dr. Armache's Research Interest: Mechanisms and functions of
ATP-dependent chromatin remodeling complexes and their place
in genome regulation
Dr. Babitzke's Research Interest: Regulation of gene expression
by RNA structure and RNA-binding proteins.
Dr. Bai's Research Interest: Chromatin structure and its role in
gene regulation.
Dr. Ferry's Research Interest: The study the enzymology and
molecular biology of anaerobic microbes from the Archaea
domain.
Dr. Gilmour's Research Interest: We use Drosophila as a model
system for employing a multifaceted approach to study
mechanisms of transcriptional regulation.
Dr. Gu's Research Interest: The utilization of biochemical,
molecular genetics, and spectroscopic approaches to
decipher mechanisms of cellulose biosynthesis.
Dr. Hardison's Research Interest: Epigenetic and genomic
approaches for the systematic study of eukaryotic gene
regulation.
Dr. Keiler's Research Interest: Protein quality control, ribosome
rescue, and new antibiotics.
Dr. Lai's Research Interest: Growth Control and Cancer Genetics.
Dr. Lindner's Research Interest: The coupling of molecular
parasitology and structural biology to study the malaria
parasite.
Dr. Llinás' Research Interest: The combination of tools from
functional genomics, molecular biology, computational biology,
biochemistry, and metabolomics to understand the fundamental
molecular mechanisms underlying the development of this
parasite.
Dr. Mahony's Research Interest: We build machine learning
applications to understand how transcription factors control
cellular identity.
Dr. Miyashiro's Research Interest: We use microbial genetics,
biochemistry, and cell biology approaches to determine the
molecular mechanisms that enable bacteria to establish
symbiosis with a eukaryotic host. The model system is the
symbiosis formed between the bioluminescent bacterium Vibrio
fischeri and the Hawaiian bobtail squid Euprymna scolopes.
Our primary interests in this system include quorum sensing,
contact-dependent killing mechanisms, and sulfur metabolism.
Dr. Murakami's Research Interest: We apply cryo-EM and X-ray
crystallography techniques to reveal three-dimensional structures
of DNA and RNA polymerases for elucidating the mechanisms of
DNA replication and RNA transcription.
Dr. Okafor's Research Interest: The structural mechanisms of
signaling and regulation in protein complexes.
Dr. Paulson's Research Interest: The mechanism of tissue
regeneration using the response to anemia as a model system.
Dr. Perdew's Research Interest: The biochemical pathway of
AHR activation and characterized species difference in AHR
mediated transcriptional activation of target genes.
Dr. Peter's Research Interest: The role of the peroxisome
proliferator-activated receptors (PPARs) in the regulation
of homeostasis, toxicology and carcinogenesis.
Dr. Reese's Research Interest: Stress-induced gene expression
and UV resistance pathways, Regulation of mRNAs from birth to
death during stress responses, Targeted protein degradation
during transcriptional stress and How RNA Polymerase II contends
with barriers throughout the genome.
Dr. Showalter's Research Interest: The use of solution
nuclear magnetic resonance (NMR) spectroscopy, in combination
with thermodynamic analysis, chemical biology, and cellular
assays to advance understanding of protein function.
Dr. Tan's Research Interest: The understanding of how genes
are regulated by combining genetic, biochemical and structural
descriptions.
